Dr. Sergio Gomez Grana

Assistant Professor, Dept. Of Physical Chemistry, University of Vigo, Spain.

Title: Microfluidics for nanoparticles self-assembly structures.



Microfluidic platforms allow generating a highly-ordered assembly of uniform gold nanoparticles inside their microchannels through the pervaporation of the solvent (Figure 1A). Furthermore, the microfluidic approach enables the fabrication of uniform assemblies of any dimension or morphology studied by SAXS.Surface-enhanced Raman spectroscopy, SERS, is an advanced analytical technique that can be used for the ultrasensible detection of analytes since it offers orders of magnitude increases in Raman signals. It occurs at the surface of a plasmon surface mainly due to the presence of strong electromagnetic fields generated after the plasmon excitation. Moreover, this effect could be more intense in the case of hierarchical nanoparticles assemblies due to an antenna effect as demonstrated by recent simulations.While the plasmonic substrates made by drop-casting show poor uniformity that limits their potential plasmonic applications, the microfluidic approach gives rise to platforms with highly uniform and intense SERS activity (being both key parameter to achieve quantitative analysis and low detection limits (LOD). Herein we will show the fabrication and characterization of plasmonic platforms fabricated using Au octahedral nanoparticles synthesized through a wet chemical method. Besides, the sensing capabilities of the platforms will be analyzed by investigating the SERS efficiency using different Raman active analytes. For instance, experiment performed with Crystal Violet showed a LOD of 100 zM, which is several orders of magnitude lower than those found in the literature. Additionally, by assembling a 3D silica supercrystal before the 3D plasmonic supercrystal we demonstrated its potential applicability as microfluidic liquid chromatography-chip with SERS-based sensing capabilities.


Dr Gómez Graña presently working as Asst. Prof at Dept. Of Physical Chemistry, University of Vigo, Spain. Earlier he worked as Post Doctoral Research Associate at ICMB in the University of Bordeaux in France and as Asist. Prof of the Inorganic chemistry department at Unviersidad Complutense, Spain. He received his doctoral degree in the year 2013 from the University of Vigo. His research prime objective is to obtain nanoparticles self assembled materials for analytes ultradetection. To his credit he has published 23 articles in various international peer reviewed and high impact journals.

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